News & Events
- 22 April 2016: InnovCrete Seminar » Drug Design via XRPD: From a protein microcrystalline sample to experimental powder diffraction data and the derived structural model, IMBB-FORTH, Heraklion, Crete
- 22 April 2016: InnovCrete Seminar » How do proteins evolve? , IMBB-FORTH, Heraklion, Crete
- 20 April 2016: InnovCrete Seminar » From Biological Self-Assembly to Novel Peptide Nanostructures of Unique Mechanical, Optical, Piezoelectric and Semiconductive Properties , IMBB-FORTH, Heraklion, Crete
- 14 April 2016: Workshops » Regional Workshop on Research Funding opportunities, IMBB-FORTH, Heraklion, Crete
- Introduction Prof. Michael Kokkinidis (IMBB-FORTH)
- "Marie Curie Programs as a launch pad for research based mobility in Structural Biology" Artemis Saitakis, Director, STEP-C
- H2020/SME Instrument : Time for exciting ventures in Structural Biology Maria Makridaki, HELP-FORWARD NETWORK/FORTH
- “Health, demographic change and well-being- Call for proposals 2016-2017” Panagiotis Ignatiadis, HELP-FORWARD NETWORK/FORTH
- European Innovation Partnership in Active Aging Panagiotis Ignatiadis, HELP-FORWARD NETWORK/FORTH
- Closing the gap between research centers and SMEs : The H2020/ SME Innovation Associate Scheme Iraklis Karantonis, HELP-FORWARD NETWORK/FORTH
- 29-30 October 2015: Workshops » Innovation Management & Awareness and Innovation Capacity Building, IMBB-FORTH, Heraklion, Crete
- Welcome Address, M. Kokkinidis (IMBB-FORTH)
- Prof. Yiannis Bakouros, University of W. Macedonia | "From Research Results to Innovative Products, Innovation Capacity Building" , "Innovation and Assets Management"
- Artemis Saitakis, Director, Science & Technology Park of Crete| "Valuation and Negotiation of Intellectual Assets"
- Artemis Saitakis, Director, Science & Technology Park of Crete| "IPR MANAGEMENT IN HORIZON 2020"
- George Papamichail, Science & Technology Park of Crete | "Together for start-up"
- Kostas Abatzis, Hellenic Industrial Property Organization | "Protection of bio inventions"
- Kostas Abatzis, Hellenic Industrial Property Organization | "Intellectual Property Strategies"
- Kostas Abatzis, Hellenic Industrial Property Organization Crete | "Searches for inventions in International Databases"
- FORTH/ PRAXI Network | Enterprise European Network (EEN)
- 8 July 2015: Seminar » Anastasia Gazi, Type III secretion systems: four decades of research, IMBB-FORTH, Heraklion, Crete
- 16-18 February 2015: Workshop » BiosCrete2015: Acoustic & optical systems for studying biomolecular interactions, IMBB-FORTH, Heraklion, Crete Program
- 21 October 2014: An Information Day on the Research PPPs will take place on 21 October 2014 in Brussels. The aim of the event is to give the research community an overview of ongoing activities, and to support the preparation of proposals for the 2015 calls. The info day will also offer plenty of opportunities for networking. More information
- 19-21 September 2014: Current Trends in Structural Biology & 7th Meeting of the Hellenic Crystallography Association, IMBB-FORTH, Heraklion, Crete Website, Poster
- 30 June - 4 July 2014: ParaMet Summer School, Computational Sciences in Drug Discovery, FORTH Institute, Heraklion, Crete Information
- 29 May 2014: Seminar » P. Filippakopoulos, Targeting the Epigenetic Readout of Acetyl-Lysine, IMBB-FORTH, Heraklion, Crete
- 31 March 2014: Workshop » Financial Instruments for Research Funding 2014-2020, IMBB-FORTH, Heraklion, Crete
- 14 March 2014: Seminar » J. Kjems, The expanding family of non-coding RNAs -- increasing complexity of gene regulation and new opportunities in nano medicine
- 28 February 2014: Seminar » P. Pavlidis, Studying DNA to learn about evolutionary history... or to say fairy tales
- 30-31 May 2013: InnovCrete Meeting, IMBB-FORTH, Heraklion, Crete
- 18 December 2012: Open Event at FORTH
Prof. Irene Margiolaki, Patras University, GREECE
Friday, April 22nd, 2016 @ 13:00
Host: M. Kokkinidis
The development of the X-ray powder diffraction (XRPD) methods and algorithms, has already allowed for the structural characterization of a range of proteins and has been established by our group as a useful complementary technique to the traditional single crystal diffraction techniques. Protein polycrystalline samples consist of a large number of randomly oriented microcrystals. They often form in a short period of time and under different conditions of physico - chemical environment. To date, our studies on Urate Oxidase and complexes of human insulin with organic ligands, revealed a high degree of polymorphism, as well as crystalline polymorphs which were not previously identified probably due to the lack of adequate tools to characterize microcrystalline protein precipitates. The aim of this talk is to describe the frontier of powder diffraction as it begins to make a significant impact on structural biology. Issues which will be discussed include: (a) application of the molecular replacement technique and structure refinements of selected proteins associated with pharmaceutical interest (b) high throughput investigations such as crystal screening andphase diagram mapping and (c) ligand binding.
Prof. Dan S. Tawfik, Weizmann Institute of Science, Israel
Friday, April 22nd, 2016 @ 12:00
Host: M. Kokkinidis
I will briefly describe our insights regarding how new enzymatic functions evolve, via gradual, small changes in sequence, and while preserving the overall structure (fold) and active-site architecture. However, the mechanisms underlying these evolutionary /micro-/transitions do not explain the /macro/ evolutionary transitions – how completely new folds emerge, let alone how the very first protein(s) evolve. The latter are thought to have emerged from short polypeptides. I will describe our findings with respect to how functional, globular proteins may emerge from short peptides.
Prof. Ehud Gazit, Tel Aviv University, ISRAEL
Friday, April 20, 2016 @ 14:00
Host: M. Kokkinidis
Bio-inspired nanotechnology is a key direction in the field of molecular self-assembly. Concept and notions from biological self-assembly allow the design and fabrication of nanomaterials, while molecular self-assembly paradigm could be applied to biological systems. Our works on the mechanism of aromatic peptide self-assembly, lead to the discovery that aromatic peptides, as short as dipeptides, self-assembles into peptide nanotubes with a remarkable physical properties We recently extended our studied to single amino acids and metabolites. We established the concept that even these entities can form well-ordered assemblies with amyloid like properties including ultrastructural morphology, toxicity leading to apoptosis, ThT-binding, and Congo-red birefringence.
The workshops are organized in the framework of the EU/REGPOT project InnovCrete coordinated by Prof. M. Kokkinidis (IMBB/FORTH & UoC/Dept. of Biology).
Please submit your registration using the attached forms by October 27th, 2015. The workshops will take place 29-30 October 2015 (final agenda is attached) at the Science and Technology Park of Crete (STEP-C), Building B, Meeting Room 211, 1st floor.
Because the number of the participants to the workshopsis limited to 30, it is highly recommended that you send back the completed form a.s.a.p.
Registration form, Agenda
Lab. d’Enzymologie et Biochimie Structurales,
CNRS, Gif-sur-Yvette, France
Host: M. Kokkinidis
University Research Lecturer,
Wellcome Trust Career Development Fellow
Structural Genomics Consortium & Ludwig Institute of Cancer Research
Nuffield Department of Clinical Medicine, University of Oxford
Welcome Address, M. Kokkinidis (IMBB-FORTH)
Horizon2020 financial instruments for research infrastructures, J. Taddei (European Commission, DG Research & Innovation, Brussels)
Regional Innovation Strategy of Crete for the period 2014-2020, M. Kassotaki, Director, Intermed (Managing Authority, Region of Crete)
Leveraging venture capital to bring projects from the lab to the market, G. Kasselakis (Openfund)
Technology Transfer and exploitation of research results, A. Saitakis, Director (Science Technology Park of Crete)
Director of Interdisciplinary Nanoscience Center (iNANO)
Director of Lundbeck Nanomedicine Center (LUNA)
Interdisciplinary Nanoscience Center (iNANO)
Department of Molecular Biology and Genetics Aarhus University, Denmark